MLB 08 The Show [BCUS98141]

Sadly I don't think the game is playable yet. It reliably hangs after a while, sometimes 10 minutes sometimes 20 or more but it always happens. Can't finish a full game that way. I tried with the reported playable version 7916 and with the latest 8385 but it always happens. I tried with LLVM and ASMJIT, tried with TSX on/off and various other settings but it always happens.
Edit: Just to add i5 8500, RX 470, tried it on a Windows 10 and on Ubuntu with OpenGL

Have you tried with vulkan? I never had any issues with vulkan and was able to play multiple games in a row with no hiccups