Metal Gear Solid 4: Guns of Patriots [BLES00246]

I'm using 0.0.12.11000.
I've an i9 10k9, nvidia rtx 2080 ti.
It costed some puzzling, but ...
Both on LLVM,
enable thread shedule:yes
lower spu:nu
enable spu loop:yes
spu cache:yes
accurate float:NO
spu block sizeafe
preffered spu:auto
gpu:vulkan
aspect:16:9
framelimit:off
ansisotropic:auto
anti-alias:auto
resolution:1280x720
resolution scale: 50 (default)
resolution scale threshold:1 (default)
shader mode:async (multi threaded)
additional settings:
multithreaded RSX:yes, rest NO!
advanced:
debug console:no
accurate llvm:yes (disabled to control)
accurate rsx:no
PPU LLVM: YESS
silence all:no
advanced gpu:
the 3 buffers enabled
brings me to actually being able to play the game, without stuttering sound on a avg framerate between 25-40 and runs actually pretty descent, better then i expected of the fps.
LOG not included, didn't see the use.
except for next line:
E {PPU[0x1000001] Thread (MGS4 MAIN) [0x00c454ec]} SYS: '_sys_lwmutex_lock' failed with 0x80010005 : CELL_ESRCH [1]

the mutex fails more often then once, how less speedproblems u've how less it occurs.
When a load doesn't reload but u hang, restart the emulator. It has been my salvation several times now!