Per Game Controller Profile Issue

When I try to configure a controller setup per game the profile option is always greyed out. I have an RCM adaptor for my Les Paul guitar which is already saved to a profile. I don't want to keep change from this to a controller when switching to different games.

Any ideas?

This is normal, if you wish to use multiple profiles then use the global controller configuration.

This is normal, if you wish to use multiple profiles then use the global controller configuration.

Any recommended threads or instructions for this before I jump down the rabbit hole?